The Naranjo algorithm can be used to assess the liklihood that a change in clinical status is the result of an ADR rather than the result of other factors such as progression of disease. Answer each of the ten items in the assessment and enter the value of the answer in the column labelled Score. Sum the scores of the ten items to determine the total score, and apply the interpretation rules that appear at the bottom of the page.
Interpretation of the Total Score
Total scores of 9 or more mean that an ADR is highly probable.
Scores from 5 to 8 mean that an ADR is probable.
Scores from 1 to 4 that an ADR is possible.
Scores of zero or less mean that an ADR is doubtful.
Monday, June 18, 2007
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